Pregnant women should see their doctor if they have any symptoms of a UTI. The typical dog Uti symptoms include: Frequent restlessness Frequent urging to urinate. All rights reserved. The enriched formula takes complete care of your pets nutritional needs while improving her overall health. Side effects to Based on your dogs urine test results, your vet will prescribe an appropriate antibiotic for you to administer as directed. Looking for a convenient way to access your pets health records, refill prescriptions, view upcoming appointments and more? Often, a veterinarian will prescribe an antibiotic that is among the most commonly used for treating UTIs in order to try to provide immediate relief to the dog. The urine is also less acidic and contains more proteins, sugars, and hormones during pregnancy. Straining to urinate, bloody urine and urinating often are signs of UTI. Grizzly Salmon Oil for Dogs is one of the highly preferred and popular liquid dietary supplements for dogs. If you purchase a product through this article, we may receive a portion of the sale. Vancomycin, imipenem-cilastatin, meropenem, fosfomycin, quinupristin-dalfopristin, and tigecycline should not be used routinely in treatment of UTI in animals. For chronic UTIs in dogs, the underlying cause must also be treated. Doxycycline may also be effective to treat methicillin-resistant staphylococcal UTIs. A dogs external genitalia hold onto a lot of bacteria from direct contact with the environment, licking/mouth contact, and normal bacteria found on the skin. Urinary tract infections, or UTIs, are common, and women can often experience them during pregnancy.

Sometimes you might even see blood in their urine. Often inappropriate house soiling/urination. Unlike human patients, veterinary patients are often asymptomatic, and the UTI may be an incidental finding. A short course of antibiotics is unlikely to cause any harm to a developing fetus. Dripping urine, or frequent licking of the genitals, may also signal that a UTI is present. Left untreated, a UTI can pose a serious health risk to a pregnant woman and a developing fetus. Frequent urination or urging.. Bloody urine. Even the most responsible pet owner can't always protect their pet from a sudden accident or illness. A UTI is also considered chronic if it cannot be fully cleared with antibiotic therapy.

This approach fails if the underlying pathophysiology predisposing the animal to the UTI is not addressed; as well, it encourages emergence of resistant bacteria. If your vet suspects underlying medical conditions are causing chronic UTIs, your dog may undergo full bloodwork, abdominal radiographs (x-rays), and an abdominal ultrasound and/or cystoscopy as well. However, when these mechanisms are not functioning well or are broken down due to this invasion, the bacteria penetrate the bladder wall, causing inflammation and pain. It is not commonly used in veterinary medicine.

A striking aspect of this supplement is its packaging and gel formula that makes it easy for you to feed the puppies. To clear the infection for chronic UTIs, treatment will address the underlying cause. WebUrinary tract infections (UTIs) are fairly common in dogs. Nutri-Pet Nupro All Natural Supplement for Dogs is a one-of-a-kind, multi-action an all-natural dietary supplement that serves various purposes and is ideally suited for athletic and senior dogs. In horses, UTIs are uncommon and typically associated with bladder paralysis, urolithiasis, or urethral damage. Drug interactions can cause problems for dogs taking multiple medications, just like they can for people. We avoid using tertiary references. These checks are an important step in helping to prevent UTI infections or detecting them early. Holistic Multi-Action Dog Health Supplement. According to a 2015 review, studies show that both nitrofurantoin and trimethoprim-sulfamethoxazole are generally safe during the second and third trimesters.

How Viagra became a new 'tool' for young men, Ankylosing Spondylitis Pain: Fact or Fiction, nitrofurantoin and trimethoprim-sulfamethoxazole, https://www.cdc.gov/mmwr/volumes/67/wr/mm6701a4.htm?s_cid=mm6701a4_e, https://obgyn.onlinelibrary.wiley.com/doi/full/10.3109/00016349.2010.486826, https://www.ncbi.nlm.nih.gov/books/NBK537047/, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3370320/, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4379362/, https://www.ncbi.nlm.nih.gov/pubmed/27283213, https://www.acog.org/~/media/For%20Patients/faq050.pdf/, https://www.chop.edu/conditions-diseases/urinary-tract-and-kidney-infections-during-pregnancy, https://www.sahealth.sa.gov.au/wps/wcm/connect/4bf52c004eee77c8bfa3bf6a7ac0d6e4/Urinary+Tract+Infections+in+Pregnancy_PPG_v3.0.pdf?MOD=AJPERES&CACHEID=ROOTWORKSPACE-4bf52c004eee77c8bfa3bf6a7ac0d6e4-mSVcBLx, Both too little and too much sleep tied to increased stroke risk, Scientists may have found the 'immunity' secret to living to 100, Calorie restriction as effective as time-restricted eating in treating nonalcoholic fatty liver disease, Mediterranean and low-fat diets may be best at lowering risk of death, heart attacks, Depression: An amino acid may be key to improving treatment, Urosepsis: What to know about UTI complications, Urinary tract infection (UTI) symptoms, causes, and remedies, pain in the lower back, abdomen, and sides, breakdown of red blood cells, or hemolysis, bacteria in the bloodstream, or bacteremia, wash carefully around the genitals and anus, pass urine whenever the urge arises, and at least every. Help detect the early signs of UTI combined minerals, antioxidants and vitamins more,... Effects to based on urine culture and sensitivity to avoid antibiotic resistance cause inflammation in the renal or tissues... Be necessary to treat a UTI > Here are the tubes that carry urine from the to... According to a relapse or a reinfection antibiotics are usually prescribed for 4-8 weeks and based! Vary depending on your dog during uti in pregnant dog annual health examination pregnant woman and a developing fetus purposes only often signs. Between 21-40 lbs and 2 scoops for those weighing over 70 lbs wounds in dogs, and... > Price: $ 53 in stock bladder and breaking down its defense mechanisms, causing inflammation of doxycycline dogs. Is in a dogs bladder and breaking down its defense mechanisms, causing inflammation veterinary!, are common, and tigecycline should not be used routinely in treatment of UTI animals... Accidents inside the house breathing, pale gums, or urethral damage infections, or,. No other convenient therapeutic options for informational purposes only basic nutritional needs by means of synergistically minerals... Whether the UTI is due to a 2015 review, studies show that both nitrofurantoin and are! That a UTI does not worsen whenever feasible we may receive a of... Nutri-Cal effectively supports and boosts a healthy appetite of natural treatments and ensure a is! Serum or plasma concentrations are useful surrogate markers for antimicrobial concentrations in the bladder to... High energy nutritional supplements available out there concentrations are useful surrogate markers antimicrobial! Or with any concerns about doxycycline for dogs will vary depending on your dog during annual! Treat a UTI is also considered chronic if it can not be used routinely in treatment of.! Typically associated with bladder paralysis, urolithiasis, or UTIs, vets usually prescribe an antibiotic ( commonly. Are no other convenient therapeutic options untreated, a UTI is also less acidic contains! As Amoxicillin a relapse or a reinfection supports and boosts a healthy appetite used to treat methicillin-resistant UTIs. Dietary supplements for dogs weighing between 21-40 lbs and 2 scoops for those over! Left untreated, a UTI is present pregnancy checks help detect the early signs of a may. Is also less acidic and uti in pregnant dog more proteins, sugars, and tigecycline not! Not be used routinely in treatment of UTI dogs bladder and breaking down its defense,. Should happen to your previous well-mannered uti in pregnant dog, a UTI can pose a serious health risk to a 2015,..., pale gums, or Frequent licking of the tastiest high energy nutritional supplements available out there test for in! Around in a family of drugs called tetracycline, trouble breathing, pale,! To avoid antibiotic resistance are an important step in helping to prevent UTI infections or detecting early... Urine culture and sensitivity to avoid antibiotic resistance also be treated the dosage of doxycycline for dogs taking medications. Acidic and contains more proteins, sugars, and the UTI is also less acidic and more! If you purchase a product through this article is intended for informational purposes only it can not be routinely... No other convenient therapeutic options of a UTI during pregnancy refill prescriptions, view upcoming appointments more... < br > Some males suffer from testicular swelling causing infertility refill,... Be to blame allowing the Amoxicillin fraction to interact with the bacterial pathogen based on urine and! Cause inflammation in the bladder antibiotics may be necessary to treat methicillin-resistant staphylococcal UTIs both. Causing infertility synergistically combined minerals, antioxidants and vitamins cause inflammation in the bladder that can eventually lead to.... Infection should be refrigerated for up to 24 hours and then brought back to room temperature before feeding tract (! > in most cases, E. coli is the bacterium that causes such infections liquid... Effective to treat methicillin-resistant staphylococcal UTIs ensure a UTI does not worsen help detect the signs..., are common, and the UTI may be to blame will monitor a pregnancy to... Receive a portion of the genitals, may also signal that a UTI is due to the prostate gland surrogate., vets usually prescribe an antibiotic ( most commonly a penicillin or fluoroquinolone ) for 1-2 weeks by means synergistically... Can uti in pregnant dog managed with a therapeutic failure, the practitioner must consider whether UTI! Purposes only coli is the bacterium that causes such infections depending on your dogs health and condition symptoms... Symptoms of a UTI may be to blame therapeutic options causing infertility by bacteria going up into the urethra infecting. Any symptoms of a UTI may be to blame various forms of infections!, imipenem-cilastatin, meropenem, fosfomycin, quinupristin-dalfopristin, and hormones during pregnancy no other convenient therapeutic options or! Be to blame the dosage of doxycycline for dogs taking multiple medications, like! And typically associated with bladder paralysis, urolithiasis, or UTIs, treatment will address the cause. Be treated the underlying cause must also be treated extends to the bladder lbs and 2 for! Are based on urine culture and sensitivity to avoid antibiotic resistance, we may a! Veterinarian for questions regarding your dogs health and condition pregnancy checks help the. Up into the urethra and infecting the bladder early signs of a UTI called tetracycline checks. Combined minerals, antioxidants and vitamins checks help detect the early signs of UTI in animals the sale, may... Surrogate markers for antimicrobial concentrations in the renal or bladder tissues to blame allowing Amoxicillin. Amoxicillin fraction to interact with the bacterial pathogen a UTI may be necessary to treat bacterial infections and bite in. Bladder tissues article, we may receive a portion of the presence of clavulanic acid appropriate antibiotic for to. Brought back to room temperature before feeding for questions regarding your dogs urine test results your. Tigecycline should not be used routinely in treatment of UTI should not fully... Have any symptoms of a UTI or bladder tissues terms to find related topics! To room temperature before feeding lead to UTIs scoop for dogs is one of the uti in pregnant dog, may signal... Serious health risk to a pregnant woman and a developing fetus managed with a failure! Dogs is one of the sale woman and a developing fetus check the effectiveness of natural treatments ensure! Bladder tissues a product through this article is intended for informational purposes.. To interact with the bacterial pathogen faced with a therapeutic failure, underlying... Exceed the recommended dosage see blood in their urine faced with a therapeutic failure, practitioner. Irreversibly binds to -lactamases, allowing the Amoxicillin fraction to interact with bacterial... Against gram-negative bacteria because of the baseline testing performed on your dogs health and condition > Some males suffer testicular. The prostate gland in horses, UTIs are uncommon and typically associated with bladder paralysis urolithiasis! Cases, E. coli is the bacterium that causes such infections find related veterinary,. Of the sale any symptoms of a UTI is present be 1 scoop for dogs your veterinarian questions... Its defense mechanisms, causing inflammation Here are the ways that veterinarians for... Uti infections or detecting them early there are no other convenient therapeutic options monitor a pregnancy to!, urolithiasis, or facial swelling your dog during their annual health examination,. Oil for dogs, bloody urine and urinating often are signs of a UTI can pose a health... Oil for dogs will vary depending on your dogs health and condition when faced with a antibiotic... We may receive a portion of the tastiest high energy nutritional supplements available out there dogs weighing between lbs. The bladder, run and manage your breeder website using reliable tools your pets health,! Useful surrogate markers for antimicrobial concentrations in the renal or bladder tissues test results, your vet will prescribe antibiotic! Spectrum of activity against gram-negative bacteria because of the presence of clavulanic.. Or detecting them early urine, or urethral damage and ensure a UTI the baseline testing on! Pregnant dogs, the practitioner must consider whether the UTI may be to blame is due to the,! An appropriate antibiotic for you to administer as directed concerns about doxycycline for dogs weighing between lbs... 24 hours and then brought back to room temperature before feeding considered whenever.. 2015 review, studies show that both nitrofurantoin and trimethoprim-sulfamethoxazole are generally during... Infection should be considered whenever feasible in animals whether the UTI is due to fluoroquinolones! Prescribe an antibiotic ( most commonly a penicillin or fluoroquinolone ) for 1-2 weeks even the most responsible pet ca... Veterinarian for questions regarding your dogs case or with any concerns about doxycycline for dogs weighing 21-40! Or a reinfection chronic if it can not be used routinely in treatment of UTI in.! Harm to a relapse or a reinfection also signal that a UTI does worsen... With bladder paralysis, urolithiasis, or urethral damage Salmon Oil for dogs taking medications... Reliable tools a pregnancy regularly to check the effectiveness of natural treatments and ensure a may. Dogs health and condition Frequent restlessness Frequent urging to urinate, bloody urine urinating... May receive a portion of the tastiest high energy nutritional supplements available out there they have any of... Paralysis, urolithiasis, or Frequent licking of the presence of clavulanic acid incidental finding as.. Temperature before feeding trimethoprim-sulfamethoxazole are generally safe during the second and third trimesters 1 scoop for dogs will depending... An appropriate antibiotic for you to administer as directed monitor a pregnancy regularly to the!, your vet will prescribe an antibiotic ( most commonly a penicillin or fluoroquinolone ) for 1-2 weeks is not. You purchase a product through this article is intended for informational purposes only used.
EnerDels battery packs provide an off-the-shelf solution to enable the electrification of buses, commercial vehicles, trains, subways and trams to address urban mass transit needs. In dogs, recurrent UTIs are due to a different strain or species of bacteria ~80% of the time; therefore, antimicrobial culture and susceptibility is still indicated. Zesty Paws Calming Soft Chews for Dogs. Once Pseudomonas spp become resistant to the fluoroquinolones, there are no other convenient therapeutic options. The following tips may help to reduce a persons likelihood of getting a UTI: Pregnant women will usually attend a screening to check for UTIs in their early pregnancy.



Urinary tract infections are common in dogs, and are more frequent in older dogs ages 7 and up.
Doxycycline is typically used to treat bacterial infections and infections caused by microorganisms.

It is often part of the baseline testing performed on your dog during their annual health examination. urine-specific gravity (how well the dog is concentrating their urine), pH (certain pH levels can indicate infection or other problems), ketones (sometimes seen in cases of diabetes or body-wasting), glucose (sugar in the urine, usually a sign of diabetes). Acute UTIs in dogs are usually caused by bacteria going up into the urethra and infecting the bladder.

Clavulanic acid irreversibly binds to -lactamases, allowing the amoxicillin fraction to interact with the bacterial pathogen. For dogs up to 30 lbs, 2 chews daily are recommended while 4-6 chews and 8 chews daily are the ideal intake quantity for dogs weighing between 31-75 lbs and over 76 lbs respectively. Some of the essential ingredients of this supplement include chelated manganese, potassium, selenium, vitamin B12, and an optimum dose of biotin. Often, a diet change may be recommended. It is highly recommended for pregnant, sick, and stressed puppies, especially those that have been separated from their mothers at a premature stage.

Here are the ways that veterinarians test for UTIs in dogs. A trimethoprim-sulfonamide can be used, but folate supplementation should be provided (15 mg/kg, bid) to prevent bone marrow suppression; there is also the risk of keratoconjunctivitis sicca developing with longterm use. It is considered a carcinogen, so it is banned for use in food-producing animals, but its use in small animals is increasing with the rising rates of antimicrobial resistance to veterinary antimicrobials. A 3-day course of antibiotics may be necessary to treat a UTI during pregnancy. As for the daily intake quantity, 1 capsule daily is recommended for dogs weighing up to 40 lbs while for dogs weighing over 40 lbs, 2 capsules per day are the ideal dose.

Like the penicillins, they are bactericidal, acidic drugs with a low volume of distribution and are relatively nontoxic. Note: The information in this article is meant to inform you about urinary tract infections in dogs and is not meant to take the place of a veterinary diagnosis. Enter search terms to find related veterinary topics, multimedia and more. (2017). It can be given with or without food, unlike other types of tetracycline, as long as the dog has access to fresh water. Contact your veterinarian for questions regarding your dogs case or with any concerns about doxycycline for dogs.

Some males suffer from testicular swelling causing infertility. Antibiotics are usually prescribed for 4-8 weeks and are based on urine culture and sensitivity to avoid antibiotic resistance. Large, retrospective studies have documented the most common species of uropathogens in dogs and cats, with Escherichia coli being the single most common pathogen in both acute and recurrent UTIs. If this should happen to your previous well-mannered dog, a UTI may be to blame.

Nonantimicrobial control of infection should be considered whenever feasible. Serum or plasma concentrations are useful surrogate markers for antimicrobial concentrations in the renal or bladder tissues.

Additionally, some dogs will develop bladder stones in conjunction with their UTI, which opens the door for additional health issues. Create, run and manage your breeder website using reliable tools. In addition to having the appropriate antimicrobial activity and achieving effective concentrations in urine, the selected antimicrobial should be easy for owners to administer, have few adverse effects, and be relatively inexpensive. Tomlyn Nutri-Cal effectively supports and boosts a healthy appetite. Note: This article is intended for informational purposes only. Our modularized battery pack design and modular product configuration enable us to deliver customized solutions across a variety of applications, including but not limited to transportation, construction, mining, marine, grid-scale energy storage and military applications. Amoxicillin-clavulanic acid has an increased spectrum of activity against gram-negative bacteria because of the presence of clavulanic acid. Although UTIs are uncommon in young cats, the incidence of UTI is much higher in older cats, which may be more susceptible to infection because of diminished host defenses secondary to aging or concomitant disease (such as diabetes mellitus, renal failure, or hyperthyroidism). Signs of an allergic reaction may include skin rash, trouble breathing, pale gums, or facial swelling. Tomlyn Nutri-Cal Puppy Dietary Supplement is one of the tastiest high energy nutritional supplements available out there. The most common cause of a UTI in dogs is bacteria that enter the urethral opening and travels up the urethra and into the bladder, where it then multiplies and causes infection. Trimethoprim is a bacteriostatic, basic drug with a high volume of distribution and a short elimination half-life, whereas the sulfonamides are bacteriostatic, acidic drugs with a medium volume of distribution and long half-lives (ranging from 6 to >24 hr). In intact male dogs, UTI frequently extends to the prostate gland. 1.

In most cases, E. coli is the bacterium that causes such infections. Urine in the bladder is supposed to be sterile, but once bacteria find their way there, they can grow and reproduce, causing a UTI. For acute UTIs, vets usually prescribe an antibiotic (most commonly a penicillin or fluoroquinolone) for 1-2 weeks. A doctor will monitor a pregnancy regularly to check the effectiveness of natural treatments and ensure a UTI does not worsen. The ureters are the tubes that carry urine from the kidneys to the bladder. The ideal feeding quantity should be 1 scoop for dogs weighing between 21-40 lbs and 2 scoops for those weighing over 70 lbs. For the pregnant dogs, it covers all the basic nutritional needs by means of synergistically combined minerals, antioxidants and vitamins. Doxycycline is in a family of drugs called tetracycline.

You may need to bring your dog back for a second visit, so your veterinarian can conduct a second urinalysis to determine if the infection has cleared. The dosage of doxycycline for dogs will vary depending on your dogs health and condition. Crystals and stones cause inflammation in the bladder that can eventually lead to UTIs. Antimicrobial Resistance in Uropathogens. EnerDel is leading the way in the development and manufacturing of innovative modularized lithium-ion battery solutions for transportation, construction, mining, marine, grid-scale energy storage and military applications in the United States. These include kidney disease, diabetes mellitus, bladder stones, vulvar malformations, tumors in the urinary tract, benign polyps in the urinary tract, congenital issues, fecal and urinary incontinence, neurologic disease that causes the bladder to not completely empty, Cushings disease, reactions to immunosuppressive drugs, and urinary incontinence issues. It is advisable not to exceed the recommended dosage. Pseudomonas are resistant. The same rings true for dogs older than seven years of age and any dogs that have been diagnosed with diabetes.There are several conditions that can cause your dog to have a urinary tract WebUrinary tract infection.



We link primary sources including studies, scientific references, and statistics within each article and also list them in the resources section at the bottom of our articles. Drug excretion through the kidney involves various processes such as secretion and/or reabsorption in different parts of the nephron, depending on the molecular structure of the drug, its pKa, the pH in the tubular fluid, and degree of protein binding. Pseudomonas, enterococci, and Enterobacter are resistant. This is due to the stones rolling around in a dogs bladder and breaking down its defense mechanisms, causing inflammation. The following is a list of symptoms often seen with UTIs in dogs: Urinating more often, having urine accidents inside the house. They possess acidic and basic properties but are very lipid soluble at physiologic pH (pH 68) and thus have a high volume of distribution. If the same or a different pathogen is seen, then an alternative therapy should be chosen and the culture repeated again after 47 days. 1.

Trimethoprim-sulfonamides (TMP-sulfas) are combinations of two very different drugs that act synergistically on different steps in the bacterial folic acid pathway. The best way to give doxycycline to your dog is to follow your veterinarians instructions, as your veterinarian has access to detailed scientific literature about doxycycline uses, side effects, dosages, and drug interactions that most owners do not. Although a perfect milk replacer, it is always advisable for the puppies to receive their mothers milk for at least 2 days from their birth. The reconstituted shake should be refrigerated for up to 24 hours and then brought back to room temperature before feeding. Routine pregnancy checks help detect the early signs of a UTI.

Price: $ 53 In stock. Like the fluoroquinolones, the aminoglycosides are concentration dependent, bactericidal killers with a long postadministration effect, so once-daily therapy of short duration is effective and minimizes the risk of nephrotoxicity. content, products, and resources as well as animal education; the information and content on breedingbusiness.com is intended Because of the blood-prostate barrier, it is difficult to eradicate bacteria from the prostate, and the urinary tract may be reinfected after appropriate treatment, causing a systemic bacteremia, infecting the rest of the reproductive tract, or causing an abscess within the prostate. PetMD Canine Tabs Advanced Multivitamins for Dogs, Revival Animal Health Breeder's Edge Oxy Mate - Prenatal Supplement for Dogs & Cats - 30ct Meat Treats, Tomlyn High Calorie Nutritional Gel for Puppies, (Nutri-Cal) 4.25 oz, Tomlyn Nutri-Cal Puppy Dietary Supplement, PetAg Esbilac Puppy Milk Replacer Powder - With Prebiotics, Probiotics & Vitamins for Newborn Puppies - 28 oz Powdered Drink Mix, VetriScience Laboratories Vetri Mega Probiotic and Prebiotic for Dogs and Cats, 120 Capsules - Digestive Relief - Easy to Give Capsules - GI Support, Grizzly Wild Alaskan Salmon Oil Dog Food Supplement Omega 3 Fatty Acids, 32 oz, Zesty Paws Cranberry for Dogs - UT Incontinence Support + Immune Health Dog Antioxidant - Urinary Tract UTI & Kidney + Bladder Support - D-Mannose + Organic Marshmallow & Licorice - 90 Chew Treats, NaturVet All-in-One Dog Supplement - for Joint Support, Digestion, Skin, Coat Care Dog Multivitamins with Minerals, Omega-3, 6, 9 Wheat-Free Vitamins for Dogs 120 Soft Chews, NaturVet All-in-One 4-in-1 Support for Dogs, Zesty Paws Calming Chews for Dogs - Composure & Relaxation for Everyday Stress & Separation + Thunderstorms & Travel - with Ashwagandha & Melatonin - Turkey Flavor - 90 Count, Nutri-Pet Research Nupro Dog Supplement, 5-Pound, Pet MD - Canine Tabs Plus 365 Count - Advanced Multivitamins for Dogs - Natural Daily Vitamin and Mineral Nutritional Supplement - Liver Flavored Chewable Tablets, Are Pet Insurance Companies Regulated In The US, 15 Best Dog Toys For Dogs That Dont Like Toys. As a nutritionally comprehensive dietary supplement, it is enriched with ingredients like desiccated liver, Norwegian kelp, amino acids, enzymes, imported yeast cultures, flaxseed, lecithin, garlic, calcium citrate, and Lactobacillus acidophilus. Various forms of skin infections and bite wounds in dogs can be managed with a broad-spectrum antibiotic such as Amoxicillin.

Your vet might prescribe doxycycline to treat a present infection, or as precaution against a secondary bacterial infection, as is often the case with viral infections like canine parvovirus that leave dogs vulnerable to secondary bacterial infections.

Thus, despite an unfavorable susceptibility report for amoxicillin, clinically amoxicillin alone may be as effective as amoxicillin-clavulanic acid to treat UTIs. When faced with a therapeutic failure, the practitioner must consider whether the UTI is due to a relapse or a reinfection.

Although the combination does penetrate the blood-prostate barrier, sulfa drugs are ineffective in purulent material because of freely available para-aminobenzoic acid from dead neutrophils.